Mirjam van der Burg Selected Research

Pre-B Cell Receptors

1/2019	Precursor B-cell development in bone marrow of Good syndrome patients.
2/2003	Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

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Mirjam van der Burg Research Topics

Disease

14	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2022 - 08/2007
12	Infections 01/2022 - 11/2007
5	Common Variable Immunodeficiency 01/2019 - 03/2007
4	Lymphopenia (Lymphocytopenia) 01/2022 - 11/2018
4	Agammaglobulinemia (Hypogammaglobulinemia) 01/2019 - 06/2011
4	Reinfection 01/2018 - 10/2012
4	Severe combined immunodeficiency with sensitivity to ionizing radiation 08/2012 - 02/2003
3	IgA Deficiency 05/2020 - 01/2018
3	Wiskott-Aldrich Syndrome 01/2017 - 02/2013
2	Microcephaly 12/2020 - 01/2016
2	Hyper-IgM Immunodeficiency Syndrome (Hyper-IgM Syndrome) 01/2018 - 09/2015
2	Lymphadenopathy 01/2018 - 08/2007
2	Atopic Dermatitis (Atopic Eczema) 09/2014 - 01/2009
2	X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency) 06/2014 - 07/2013
2	Neoplasms (Cancer) 05/2014 - 10/2012
2	Severe combined immunodeficiency due to adenosine deaminase deficiency 03/2014 - 08/2010
2	Primary Immunodeficiency Diseases 02/2014 - 06/2011
1	Cicatrix (Scar) 01/2022
1	22q11 Deletion Syndrome 01/2022
1	Bare lymphocyte syndrome 2 01/2022
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2021
1	Atrophy 12/2020
1	autosomal recessive 1 Spinocerebellar ataxia 12/2020
1	Seizures (Absence Seizure) 12/2020
1	Guillain-Barre Syndrome 01/2019
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2019
1	Bacterial Infections (Bacterial Infection) 01/2018
1	Rheumatoid Arthritis 01/2018
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2018
1	Virus Diseases (Viral Diseases) 01/2018
1	Discitis 01/2018
1	Turcot syndrome 01/2018
1	Tuberculosis (Tuberculoses) 09/2015
1	Lymphadenitis (Adenitis) 09/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 09/2015
1	Hashimoto Disease (Thyroiditis, Hashimoto) 06/2015
1	Brain Infarction 05/2015
1	ZAP70 deficiency 05/2015
1	Bruton type agammaglobulinemia 03/2015
1	Pneumonia (Pneumonitis) 01/2015
1	Otitis Media 01/2015
1	Down Syndrome (Down's Syndrome) 12/2014
1	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2014
1	Eczema 05/2014
1	DiGeorge Syndrome (Syndrome, DiGeorge) 04/2014
1	Arthritis (Polyarthritis) 01/2013
1	Hepatitis B 01/2013
1	Nijmegen Breakage Syndrome 10/2012
1	Diarrhea 08/2012
1	variable Immunodeficiency syndrome 06/2011
1	Eosinophilia 01/2009

Drug/Important Bio-Agent (IBA)

8	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 02/2003
7	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 04/2002
6	Immunoglobulin G (IgG)IBA 01/2019 - 06/2011
5	Immunoglobulins (Immunoglobulin)IBA 06/2020 - 04/2002
5	Immunoglobulin A (IgA)IBA 05/2020 - 06/2011
5	Immunoglobulin IsotypesIBA 01/2019 - 06/2011
5	AntigensIBA 01/2019 - 10/2004
4	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2021 - 02/2003
3	Immunoglobulin M (IgM)IBA 01/2018 - 12/2014
3	Proteins (Proteins, Gene)FDA Link 05/2015 - 07/2002
3	CytokinesIBA 07/2013 - 08/2007
2	Biomarkers (Surrogate Marker)IBA 11/2021 - 12/2020
2	Recombinases (Recombinase)IBA 06/2020 - 08/2007
2	VaccinesIBA 01/2019 - 01/2013
2	Pre-B Cell ReceptorsIBA 01/2019 - 02/2003
2	Polysaccharides (Glycans)IBA 01/2018 - 01/2013
2	Immunoglobulin E (IgE)IBA 09/2014 - 01/2009
2	Adenosine DeaminaseIBA 03/2014 - 08/2010
2	AntibodiesIBA 06/2011 - 10/2004
2	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 12/2009 - 01/2009
1	Attenuated VaccinesIBA 01/2022
1	Codon (Codons)IBA 01/2022
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 12/2020
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2019
1	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2018
1	Biological ProductsIBA 01/2018
1	AutoantibodiesIBA 01/2018
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2018
1	Nonsense Codon (Nonsense Mutation)IBA 01/2017
1	Cytidine DeaminaseIBA 09/2015
1	Agammaglobulinaemia Tyrosine KinaseIBA 03/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2015
1	CD40 Ligand (CD40L)IBA 09/2014
1	Complementary DNA (cDNA)IBA 06/2014
1	Wiskott-Aldrich Syndrome ProteinIBA 05/2014
1	Interleukin-2 Receptors (IL 2 Receptor)IBA 04/2014
1	Protein Kinases (Protein Kinase)IBA 04/2014
1	Complementarity Determining Regions (Complementarity Determining Region)IBA 04/2014
1	DNA-Binding Proteins (DNA Binding Protein)IBA 06/2011
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2010
1	DNA-Activated Protein KinaseIBA 12/2009
1	A-Form DNA (A-DNA)IBA 01/2009
1	Phosphotransferases (Kinase)IBA 01/2009

Therapy/Procedure

3	Hematopoietic Stem Cell Transplantation 01/2021 - 03/2007
3	Therapeutics 01/2018 - 03/2007
2	Antibiotic Prophylaxis 01/2022 - 01/2018
2	Transplantation 01/2017 - 08/2012
1	Ligation 01/2016
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 06/2015